| Host: |
Goat |
| Applications: |
Pep-ELISA |
| Reactivity: |
Human/Mouse/Dog/Pig/Cow |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-SLC1A7 (Internal) is suitable for use in ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
Peptide ELISA: antibody detection limit dilution 1:32000.WB: Preliminary experiments gave an approx 100kDa band in Human Heart lysates after 1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
SLC1A7 |
| Gene ID: |
6512 |
| Uniprot ID: |
EAA5_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_006662.3 |
| Immunogen Sequence: |
RTRRLSPQEISYFQ |
| Function | Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Acts primarily as an inhibitory glutamate-gated chloride channel being a major inhibitory presynaptic receptor at mammalian rod bipolar cell axon terminals. Glutamate binding gates a large Cl(-) conductance that mediates inhibition, affecting visual processing in the retina. |
| Protein Name | Excitatory Amino Acid Transporter 5Retinal Glutamate TransporterSolute Carrier Family 1 Member 7 |
| Database Links | Reactome: R-HSA-210500Reactome: R-HSA-425393 |
| Cellular Localisation | Photoreceptor Inner Segment MembraneMulti-Pass Membrane ProteinSynaptic Cell MembraneLocated In Both Cone And Rod Photoreceptor Terminals And In Axon Terminals Of Rod Bipolar Cells |
| Alternative Antibody Names | Anti-Excitatory Amino Acid Transporter 5 antibodyAnti-Retinal Glutamate Transporter antibodyAnti-Solute Carrier Family 1 Member 7 antibodyAnti-SLC1A7 antibodyAnti-EAAT5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
