| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC16A3 |
| Gene ID: | 9123 |
| Uniprot ID: | MOT4_HUMAN |
| Immunogen Region: | 410-465 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 410-465 of human MCT4/SLC16A3 (NP_004198.1). |
| Immunogen Sequence: | IRKKPKEPQPEVAAAEEEKL HKPPADSGVDLREVEHFLKA EPEKNGEVVHTPETSV |
| Tissue Specificity | Highly expressed in skeletal muscle. |
| Function | Proton-dependent transporter of monocarboxylates such as L-lactate and pyruvate. Plays a predominant role in L-lactate efflux from highly glycolytic cells. |
| Protein Name | Monocarboxylate Transporter 4Mct 4Solute Carrier Family 16 Member 3 |
| Database Links | Reactome: R-HSA-210991Reactome: R-HSA-433692 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell MembranePlasma Membrane Localization Is Dependent Upon The Bsg/Mct4 InteractionBasolateral Sorting Signals (Blss) In C-Terminal Cytoplasmic Tail Ensure Its Basolateral Expression In Polarised Epithelial Cells |
| Alternative Antibody Names | Anti-Monocarboxylate Transporter 4 antibodyAnti-Mct 4 antibodyAnti-Solute Carrier Family 16 Member 3 antibodyAnti-SLC16A3 antibodyAnti-MCT3 antibodyAnti-MCT4 antibody |
Information sourced from Uniprot.org