Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Monocarboxylate transporter 8 (112-161 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000ELISA 1:40000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | SLC16A2 |
Gene ID: | 6567 |
Uniprot ID: | MOT8_HUMAN |
Immunogen Region: | 112-161 aa |
Specificity: | MCT8 Polyclonal Antibody detects endogenous levels of MCT8 protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human SLC16A2 at the amino acid range 112-161 |
Function | Specific thyroid hormone transmembrane transporter, that mediates both uptake and efflux of thyroid hormones across the cell membrane independently of pH or a Na(+) gradient. Major substrates are the iodothyronines T3 and T4 and to a lesser extent rT3 and 3,3-diiodothyronine (3,3'-T2). Acts as an important mediator of thyroid hormone transport, especially T3, through the blood-brain barrier (Probable). |
Protein Name | Monocarboxylate Transporter 8Mct 8Monocarboxylate Transporter 7Mct 7Solute Carrier Family 16 Member 2X-Linked Pest-Containing Transporter |
Database Links | Reactome: R-HSA-879518 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinApical Cell Membrane |
Alternative Antibody Names | Anti-Monocarboxylate Transporter 8 antibodyAnti-Mct 8 antibodyAnti-Monocarboxylate Transporter 7 antibodyAnti-Mct 7 antibodyAnti-Solute Carrier Family 16 Member 2 antibodyAnti-X-Linked Pest-Containing Transporter antibodyAnti-SLC16A2 antibodyAnti-MCT7 antibodyAnti-MCT8 antibodyAnti-XPCT antibody |
Information sourced from Uniprot.org