Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Solute carrier family 12 member 2-chloride cotransporter 2 is suitable for use in Western Blot and ELISA research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | SLC12A2 |
Gene ID: | 6558 |
Uniprot ID: | S12A2_HUMAN |
Specificity: | S12A2 Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: | Synthesized peptide derived from part of the human protein |
Post Translational Modifications | Phosphorylated at Thr-203, Thr-207 and Thr-212 by OXSR1/OSR1 and STK39/SPAK downstream of WNK kinases (WNK1, WNK2, WNK3 or WNK4), promoting its activity. |
Function | Cation-chloride cotransporter which mediates the electroneutral transport of chloride, potassium and/or sodium ions across the membrane. Plays a vital role in the regulation of ionic balance and cell volume. |
Protein Name | Solute Carrier Family 12 Member 2Basolateral Na-K-Cl SymporterBumetanide-Sensitive Sodium-(Potassium-Chloride Cotransporter 2Bsc2Na-K-2cl Cotransporter 1Hnkcc1 |
Database Links | Reactome: R-HSA-426117 |
Cellular Localisation | Basolateral Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Solute Carrier Family 12 Member 2 antibodyAnti-Basolateral Na-K-Cl Symporter antibodyAnti-Bumetanide-Sensitive Sodium-(Potassium-Chloride Cotransporter 2 antibodyAnti-Bsc2 antibodyAnti-Na-K-2cl Cotransporter 1 antibodyAnti-Hnkcc1 antibodyAnti-SLC12A2 antibodyAnti-NKCC1 antibody |
Information sourced from Uniprot.org