Anti-SLC12A2 antibody (Internal) (STJ72112)

SKU:
STJ72112-100
£312.50
Free Shipping
Processing The item has been added

Host: Goat
Applications: Pep-ELISA/IHC/IF/FC
Reactivity: Human/Mouse/Rat/Dog/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Goat polyclonal antibody anti-SLC12A2 (Internal) is suitable for use in ELISA, Immunohistochemistry, Immunofluorescence and Flow Cytometry research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: Peptide ELISA: antibody detection limit dilution 1:64000.
IHC: In paraffin embedded Human Colon shows membranous staining. Recommended concentration: 3.75µg/ml.
IF: Strong expression of the protein seen in the cytoplasm/vesicles of HeLa cells
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: SLC12A2
Gene ID: 6558
Uniprot ID: S12A2_HUMAN
Immunogen Region: Internal
Accession Number: NP_001037.1; NP_001243390.1
Immunogen Sequence: NALQHSIRLSGVEDH
Post Translational Modifications Phosphorylated at Thr-203, Thr-207 and Thr-212 by OXSR1/OSR1 and STK39/SPAK downstream of WNK kinases (WNK1, WNK2, WNK3 or WNK4), promoting its activity.
Function Cation-chloride cotransporter which mediates the electroneutral transport of chloride, potassium and/or sodium ions across the membrane. Plays a vital role in the regulation of ionic balance and cell volume.
Protein Name Solute Carrier Family 12 Member 2
Basolateral Na-K-Cl Symporter
Bumetanide-Sensitive Sodium-(Potassium-Chloride Cotransporter 2
Bsc2
Na-K-2cl Cotransporter 1
Hnkcc1
Database Links Reactome: R-HSA-426117
Cellular Localisation Basolateral Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Solute Carrier Family 12 Member 2 antibody
Anti-Basolateral Na-K-Cl Symporter antibody
Anti-Bumetanide-Sensitive Sodium-(Potassium-Chloride Cotransporter 2 antibody
Anti-Bsc2 antibody
Anti-Na-K-2cl Cotransporter 1 antibody
Anti-Hnkcc1 antibody
Anti-SLC12A2 antibody
Anti-NKCC1 antibody

Information sourced from Uniprot.org