• Western blot analysis of extracts of mouse fetal muscle, using SKI antibody (STJ11100892). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST.

Anti-SKI antibody (700-800) (STJ11100892)

SKU:
STJ11100892

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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SKI
Gene ID: 6497
Uniprot ID: SKI_HUMAN
Immunogen Region: 700-800
Specificity: A synthetic peptide corresponding to a sequence within amino acids 650-728 of human SKI (NP_003027.1).
Immunogen Sequence: CDKGCEAGRLRAKYSAQIED LQVKLQHAEADREQLRADLL REREAREHLEKVVKELQEQL WPRARPEAAGSEGAAELEP
Post Translational Modifications Ubiquitinated by ARK2C, promoting proteasomal degradation, leading to enhance the BMP-Smad signaling.
Function May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Functions as a repressor of TGF-beta signaling.
Protein Name Ski Oncogene
Proto-Oncogene C-Ski
Database Links Reactome: R-HSA-201451
Reactome: R-HSA-2173795
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Ski Oncogene antibody
Anti-Proto-Oncogene C-Ski antibody
Anti-SKI antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance