Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
Purification: |
Affinity purification |
Concentration: |
Lot specific |
Dilution Range: |
WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SKI |
Gene ID: |
6497 |
Uniprot ID: |
SKI_HUMAN |
Immunogen Region: |
700-800 |
Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 650-728 of human SKI (NP_003027.1). |
Immunogen Sequence: |
CDKGCEAGRLRAKYSAQIED LQVKLQHAEADREQLRADLL REREAREHLEKVVKELQEQL WPRARPEAAGSEGAAELEP |
Post Translational Modifications | Ubiquitinated by ARK2C, promoting proteasomal degradation, leading to enhance the BMP-Smad signaling. |
Function | May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Functions as a repressor of TGF-beta signaling. |
Protein Name | Ski OncogeneProto-Oncogene C-Ski |
Database Links | Reactome: R-HSA-201451Reactome: R-HSA-2173795 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Ski Oncogene antibodyAnti-Proto-Oncogene C-Ski antibodyAnti-SKI antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance