Host: |
Goat |
Applications: |
Pep-ELISA/WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Goat polyclonal antibody anti-SIGLEC6 (Internal) is suitable for use in ELISA and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: |
0.5 mg/mL |
Dilution Range: |
Peptide ELISA: antibody detection limit dilution 1:16000.WB: Experiments gave bands at approx 60kDa and 35kDa in Human Placenta lysates. These bands correspond to earlier findings with different antibodies from other sources. This protein has a |
Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: |
SIGLEC6 |
Gene ID: |
946 |
Uniprot ID: |
SIGL6_HUMAN |
Immunogen Region: |
Internal |
Accession Number: |
NP_001236.4; NP_942142.3; NP_942143.3 |
Specificity: |
This antibody is expected to recognize all reported isoforms (NP_001236.4; NP_942142.3; NP_942143.3). |
Immunogen Sequence: |
KWMKYGYTSSK |
Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
Protein Name | Sialic Acid-Binding Ig-Like Lectin 6Siglec-6Cd33 Antigen-Like 1Cdw327Obesity-Binding Protein 1Ob-Bp1Cd Antigen Cd327 |
Database Links | Reactome: R-HSA-198933 |
Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
Alternative Antibody Names | Anti-Sialic Acid-Binding Ig-Like Lectin 6 antibodyAnti-Siglec-6 antibodyAnti-Cd33 Antigen-Like 1 antibodyAnti-Cdw327 antibodyAnti-Obesity-Binding Protein 1 antibodyAnti-Ob-Bp1 antibodyAnti-Cd Antigen Cd327 antibodyAnti-SIGLEC6 antibodyAnti-CD33L antibodyAnti-CD33L1 antibodyAnti-OBBP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance