| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-SIGLEC6 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Experiments gave bands at approx 60kDa and 35kDa in Human Placenta lysates. These bands correspond to earlier findings with different antibodies from other sources. This protein has a |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | SIGLEC6 |
| Gene ID: | 946 |
| Uniprot ID: | SIGL6_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_001236.4; NP_942142.3; NP_942143.3 |
| Specificity: | This antibody is expected to recognize all reported isoforms (NP_001236.4; NP_942142.3; NP_942143.3). |
| Immunogen Sequence: | KWMKYGYTSSK |
| Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
| Protein Name | Sialic Acid-Binding Ig-Like Lectin 6Siglec-6Cd33 Antigen-Like 1Cdw327Obesity-Binding Protein 1Ob-Bp1Cd Antigen Cd327 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Sialic Acid-Binding Ig-Like Lectin 6 antibodyAnti-Siglec-6 antibodyAnti-Cd33 Antigen-Like 1 antibodyAnti-Cdw327 antibodyAnti-Obesity-Binding Protein 1 antibodyAnti-Ob-Bp1 antibodyAnti-Cd Antigen Cd327 antibodyAnti-SIGLEC6 antibodyAnti-CD33L antibodyAnti-CD33L1 antibodyAnti-OBBP1 antibody |
Information sourced from Uniprot.org