| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Sialic acid-binding Ig-like lectin 6 (71-120 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC-P 1:50-200ELISA 1:10000-20000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SIGLEC6 |
| Gene ID: | 946 |
| Uniprot ID: | SIGL6_HUMAN |
| Immunogen Region: | 71-120 aa |
| Specificity: | The antibody detects endogenous CD327 |
| Immunogen: | Synthetic peptide from the human protein at the amino acid range 71-120 |
| Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
| Protein Name | Sialic Acid-Binding Ig-Like Lectin 6Siglec-6Cd33 Antigen-Like 1Cdw327Obesity-Binding Protein 1Ob-Bp1Cd Antigen Cd327 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Sialic Acid-Binding Ig-Like Lectin 6 antibodyAnti-Siglec-6 antibodyAnti-Cd33 Antigen-Like 1 antibodyAnti-Cdw327 antibodyAnti-Obesity-Binding Protein 1 antibodyAnti-Ob-Bp1 antibodyAnti-Cd Antigen Cd327 antibodyAnti-SIGLEC6 antibodyAnti-CD33L antibodyAnti-CD33L1 antibodyAnti-OBBP1 antibody |
Information sourced from Uniprot.org