| Short Description : | Rabbit polyclonal SGSH (273-502) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SGSH |
| Gene ID: | 6448 |
| Uniprot ID: | SPHM_HUMAN |
| Immunogen Region: | 273-502 |
| Immunogen Sequence: | DNGIPFPSGRTNLYWPGTAE PLLVSSPEHPKRWGQVSEAY VSLLDLTPTILDWFSIPYPS YAIFGSKTIHLTGRSLLPAL EAEPLWATVFGSQSHHEVTM SYPMRSVQHRHFRLVHNLNF KMPFPIDQDFYVSPTFQDLL NRTTAGQPTGWYKDLRHYYY RARWELYDRSRDPHETQNLA TDPRFAQLLEMLRDQLAKWQ WETHDPWVCAPDGVLEEKLS PQCQPLHNEL |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 273-502 of human SGSH (NP_000190.1). |
| Post Translational Modifications | The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. |
| Function | Catalyzes a step in lysosomal heparan sulfate degradation. |
| Protein Name | N-Sulphoglucosamine SulphohydrolaseSulfoglucosamine SulfamidaseSulphamidase |
| Database Links | Reactome: R-HSA-2024096Reactome: R-HSA-2206307 |
| Cellular Localisation | Lysosome |
| Alternative Antibody Names | Anti-N-Sulphoglucosamine Sulphohydrolase antibodyAnti-Sulfoglucosamine Sulfamidase antibodyAnti-Sulphamidase antibodyAnti-SGSH antibodyAnti-HSS antibody |
Information sourced from Uniprot.org
