Anti-SETDB2 antibody (STJ191894)

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STJ191894
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-Histone-lysine N-methyltransferase SETDB2 for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ELISA
Host:Rabbit
Reactivity:Human/Rat/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
ELISA 1:5000-20000
Formulation:Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:SETDB2
Gene ID:83852
Uniprot ID:SETB2_HUMAN
Immunogen:Synthesized peptide derived from part of the human protein
Specificity:SETB2 Polyclonal Antibody detects endogenous levels of protein.
Function Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.
Protein Name Histone-Lysine N-Methyltransferase Setdb2
Chronic Lymphocytic Leukemia Deletion Region Gene 8 Protein
Lysine N-Methyltransferase 1f
Set Domain Bifurcated 2
Database Links Reactome: R-HSA-3214841
Cellular Localisation Nucleus
Chromosome
Alternative Antibody Names Anti-Histone-Lysine N-Methyltransferase Setdb2 antibody
Anti-Chronic Lymphocytic Leukemia Deletion Region Gene 8 Protein antibody
Anti-Lysine N-Methyltransferase 1f antibody
Anti-Set Domain Bifurcated 2 antibody
Anti-SETDB2 antibody
Anti-C13orf4 antibody
Anti-CLLD8 antibody
Anti-KMT1F antibody

Information sourced from Uniprot.org

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