| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SERPINA6 |
| Gene ID: |
866 |
| Uniprot ID: |
CBG_HUMAN |
| Immunogen Region: |
136-405 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 136-405 of human SERPINA6 (NP_001747.2). |
| Immunogen Sequence: |
SLELLESFSADIKHYYESEV LAMNFQDWATASRQINSYVK NKTQGKIVDLFSGLDSPAIL VLVNYIFFKGTWTQPFDLAS TREENFYVDETTVVKVPMML QSSTISYLHDAELPCQLVQM NYVGNGTVFFILPDKGKMNT VIAALSRDTINRWSAGLTSS QVDLYIPKVTISGVYDLGDV LEEMGIADLFTNQANFSRIT QDAQLKSSKVVHKAVLQLNE EGVDTAGSTGVTLNLTSKP |
| Tissue Specificity | Plasma.synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells. |
| Post Translational Modifications | N-glycosylated.binds 5 oligosaccharide chains. Glycosylation in position Asn-260 is needed for steroid binding. |
| Function | Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. |
| Protein Name | Corticosteroid-Binding GlobulinCbgSerpin A6Transcortin |
| Database Links | Reactome: R-HSA-194002Reactome: R-HSA-9757110 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Corticosteroid-Binding Globulin antibodyAnti-Cbg antibodyAnti-Serpin A6 antibodyAnti-Transcortin antibodyAnti-SERPINA6 antibodyAnti-CBG antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
