| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SERPINA6 |
| Gene ID: | 866 |
| Uniprot ID: | CBG_HUMAN |
| Immunogen Region: | 136-405 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 136-405 of human SERPINA6 (NP_001747.2). |
| Immunogen Sequence: | SLELLESFSADIKHYYESEV LAMNFQDWATASRQINSYVK NKTQGKIVDLFSGLDSPAIL VLVNYIFFKGTWTQPFDLAS TREENFYVDETTVVKVPMML QSSTISYLHDAELPCQLVQM NYVGNGTVFFILPDKGKMNT VIAALSRDTINRWSAGLTSS QVDLYIPKVTISGVYDLGDV LEEMGIADLFTNQANFSRIT QDAQLKSSKVVHKAVLQLNE EGVDTAGSTGVTLNLTSKP |
| Tissue Specificity | Plasma.synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells. |
| Post Translational Modifications | N-glycosylated.binds 5 oligosaccharide chains. Glycosylation in position Asn-260 is needed for steroid binding. |
| Function | Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. |
| Protein Name | Corticosteroid-Binding GlobulinCbgSerpin A6Transcortin |
| Database Links | Reactome: R-HSA-194002Reactome: R-HSA-9757110 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Corticosteroid-Binding Globulin antibodyAnti-Cbg antibodyAnti-Serpin A6 antibodyAnti-Transcortin antibodyAnti-SERPINA6 antibodyAnti-CBG antibody |
Information sourced from Uniprot.org