| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-SERPINA12 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 48kDa band observed in Human Adipose lysates (calculated MW of 47.2kDa according to NP_776249.1). Recommended concentration: 0.3-1µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | SERPINA12 |
| Gene ID: | 145264 |
| Uniprot ID: | SPA12_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_776249.1 |
| Immunogen Sequence: | RARWKHEFDPNVTK |
| Post Translational Modifications | Glycosylation slightly decreases affinity for heparin, but otherwise has no significant effect on KLK7 inhibitory activity or thermal stability of the protein. |
| Function | Adipokine that modulates insulin action by specifically inhibiting its target protease KLK7 in white adipose tissues. |
| Protein Name | Serpin A12Ol-64Visceral Adipose Tissue-Derived Serine Protease InhibitorVaspinVisceral Adipose-Specific Serpin |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Serpin A12 antibodyAnti-Ol-64 antibodyAnti-Visceral Adipose Tissue-Derived Serine Protease Inhibitor antibodyAnti-Vaspin antibodyAnti-Visceral Adipose-Specific Serpin antibodyAnti-SERPINA12 antibody |
Information sourced from Uniprot.org