• Western blot analysis of extracts of mouse brain, using SERPINA12 Antibody (STJ110377) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
  • Western blot analysis of extracts of mouse brain, using SERPINA12 Antibody (STJ110377) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-SERPINA12 antibody (20-320) (STJ110377)

SKU:
STJ110377

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SERPINA12 (20-320) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SERPINA12
Gene ID: 145264
Uniprot ID: SPA12_HUMAN
Immunogen Region: 20-320
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human SERPINA12 (NP_776249.1).
Immunogen Sequence: LLKPSFSPRNYKALSEVQGW KQRMAAKELARQNMDLGFKL LKKLAFYNPGRNIFLSPLSI STAFSMLCLGAQDSTLDEIK QGFNFRKMPEKDLHEGFHYI IHELTQKTQDLKLSIGNTLF IDQRLQPQRKFLEDAKNFYS AETILTNFQNLEMAQKQIND FISQKTHGKINNLIENIDPG TVMLLANYIFFRARWKHEFD PNVTKEEDFFLEKNSSVKVP MMFRSGIYQVGYDDKLSCT
Tissue Specificity Expressed in visceral adipose tissues.
Post Translational Modifications Glycosylation slightly decreases affinity for heparin, but otherwise has no significant effect on KLK7 inhibitory activity or thermal stability of the protein.
Function Adipokine that modulates insulin action by specifically inhibiting its target protease KLK7 in white adipose tissues.
Protein Name Serpin A12
Ol-64
Visceral Adipose Tissue-Derived Serine Protease Inhibitor
Vaspin
Visceral Adipose-Specific Serpin
Cellular Localisation Secreted
Alternative Antibody Names Anti-Serpin A12 antibody
Anti-Ol-64 antibody
Anti-Visceral Adipose Tissue-Derived Serine Protease Inhibitor antibody
Anti-Vaspin antibody
Anti-Visceral Adipose-Specific Serpin antibody
Anti-SERPINA12 antibody

Information sourced from Uniprot.org

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