• Western blot analysis of various lysis using Septin 6 Polyclonal Antibody diluted at 1：1000. Secondary antibody was diluted at 1:20000
  • Western blot analysis of the lysates from HeLa cells using SEPT6 antibody.
  • Western blot analysis of JK cells using Septin 6 Polyclonal Antibody diluted at 1：1000

Anti-SEPTIN6 antibody (223-272 aa) (STJ95615)

SKU:
STJ95615

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Septin-6 (223-272 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SEPTIN6
Gene ID: 23157
Uniprot ID: SEPT6_HUMAN
Immunogen Region: 223-272 aa
Specificity: Septin 6 Polyclonal Antibody detects endogenous levels of Septin 6 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human SEPT6 at the amino acid range 223-272
Function Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation.
Protein Name Septin-6
Cellular Localisation Cytoplasm
Cytoskeleton
Spindle
Chromosome
Centromere
Kinetochore
Cleavage Furrow
Midbody
Cell Projection
Cilium
Flagellum
In Metaphase Cells
Localized Within The Microtubule Spindle
At The Metaphase Plate
In Close Apposition To The Kinetochores Of The Congressed Chromosomes
In Cells Undergoing Cytokinesis
Localized To The Midbody
The Ingressing Cleavage Furrow
And The Central Spindle
Found In The Sperm Annulus
Alternative Antibody Names Anti-Septin-6 antibody
Anti-SEPTIN6 antibody
Anti-KIAA0128 antibody
Anti-SEP2 antibody
Anti-SEPT6 antibody

Information sourced from Uniprot.org

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