| Host: |
Rabbit |
| Applications: |
ELISA/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SEPT6 (370-430) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Purification: |
Affinity Purified |
| Concentration: |
0.54-0.59 µg/µl |
| Dilution Range: |
WB: 1:500DB: 1:10, 000ELISA: 1:10, 000 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Immunogen Region: |
370-430 |
| Immunogen: |
Synthetic peptide taken within amino acid region 370-430 on SEPT6 protein. |
| Function | Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation. |
| Protein Name | Septin-6 |
| Cellular Localisation | CytoplasmCytoskeletonSpindleChromosomeCentromereKinetochoreCleavage FurrowMidbodyCell ProjectionCiliumFlagellumIn Metaphase CellsLocalized Within The Microtubule SpindleAt The Metaphase PlateIn Close Apposition To The Kinetochores Of The Congressed ChromosomesIn Cells Undergoing CytokinesisLocalized To The MidbodyThe Ingressing Cleavage FurrowAnd The Central SpindleFound In The Sperm Annulus |
| Alternative Antibody Names | Anti-Septin-6 antibodyAnti-SEPTIN6 antibodyAnti-KIAA0128 antibodyAnti-SEP2 antibodyAnti-SEPT6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
