Anti-SEPT6 antibody (370-430) (STJ502911)

SKU:
STJ502911-100

£441.50
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Host: Rabbit
Applications: ELISA/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SEPT6 (370-430) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.54-0.59 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Immunogen Region: 370-430
Immunogen: Synthetic peptide taken within amino acid region 370-430 on SEPT6 protein.
Function Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation.
Protein Name Septin-6
Cellular Localisation Cytoplasm
Cytoskeleton
Spindle
Chromosome
Centromere
Kinetochore
Cleavage Furrow
Midbody
Cell Projection
Cilium
Flagellum
In Metaphase Cells
Localized Within The Microtubule Spindle
At The Metaphase Plate
In Close Apposition To The Kinetochores Of The Congressed Chromosomes
In Cells Undergoing Cytokinesis
Localized To The Midbody
The Ingressing Cleavage Furrow
And The Central Spindle
Found In The Sperm Annulus
Alternative Antibody Names Anti-Septin-6 antibody
Anti-SEPTIN6 antibody
Anti-KIAA0128 antibody
Anti-SEP2 antibody
Anti-SEPT6 antibody

Information sourced from Uniprot.org

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