| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:5000IHC-P:1:100-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SEPTIN5 |
| Gene ID: | 5413 |
| Uniprot ID: | SEPT5_HUMAN |
| Immunogen Region: | 1-369 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-369 of human Septin 5 (NP_002679.2). |
| Immunogen Sequence: | MSTGLRYKSKLATPEDKQDI DKQYVGFATLPNQVHRKSVK KGFDFTLMVAGESGLGKSTL VHSLFLTDLYKDRKLLSAEE RISQTVEILKHTVDIEEKGV KLKLTIVDTPGFGDAVNNTE CWKPITDYVDQQFEQYFRDE SGLNRKNIQDNRVHCCLYFI SPFGHGLRPVDVGFMKALHE KVNIVPLIAKADCLVPSEIR KLKERIREEIDKFGIHVYQF PECDSDEDEDFKQQDRELK |
| Tissue Specificity | Expressed at high levels in the CNS, as well as in heart and platelets (at protein level). |
| Post Translational Modifications | Phosphorylated by DYRK1A. In platelets, phosphorylated in response to thrombin, phorbol-12-myristate-13-acetate and collagen. |
| Function | Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in platelet secretion. |
| Protein Name | Septin-5Cell Division Control-Related Protein 1Cdcrel-1Peanut-Like Protein 1 |
| Cellular Localisation | CytoplasmCytoskeletonIn PlateletsFound In Areas Surrounding Alpha-Granules |
| Alternative Antibody Names | Anti-Septin-5 antibodyAnti-Cell Division Control-Related Protein 1 antibodyAnti-Cdcrel-1 antibodyAnti-Peanut-Like Protein 1 antibodyAnti-SEPTIN5 antibodyAnti-PNUTL1 antibodyAnti-SEPT5 antibody |
Information sourced from Uniprot.org