| Host: |
Rabbit |
| Applications: |
WB/IHC/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SEPT5 (1-369) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:5000IHC-P 1:100-1:200IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SEPTIN5 |
| Gene ID: |
5413 |
| Uniprot ID: |
SEPT5_HUMAN |
| Immunogen Region: |
1-369 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-369 of human Septin 5 (NP_002679.2). |
| Immunogen Sequence: |
MSTGLRYKSKLATPEDKQDI DKQYVGFATLPNQVHRKSVK KGFDFTLMVAGESGLGKSTL VHSLFLTDLYKDRKLLSAEE RISQTVEILKHTVDIEEKGV KLKLTIVDTPGFGDAVNNTE CWKPITDYVDQQFEQYFRDE SGLNRKNIQDNRVHCCLYFI SPFGHGLRPVDVGFMKALHE KVNIVPLIAKADCLVPSEIR KLKERIREEIDKFGIHVYQF PECDSDEDEDFKQQDRELK |
| Tissue Specificity | Expressed at high levels in the CNS, as well as in heart and platelets (at protein level). |
| Post Translational Modifications | Phosphorylated by DYRK1A. In platelets, phosphorylated in response to thrombin, phorbol-12-myristate-13-acetate and collagen. |
| Function | Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in platelet secretion. |
| Protein Name | Septin-5Cell Division Control-Related Protein 1Cdcrel-1Peanut-Like Protein 1 |
| Cellular Localisation | CytoplasmCytoskeletonIn PlateletsFound In Areas Surrounding Alpha-Granules |
| Alternative Antibody Names | Anti-Septin-5 antibodyAnti-Cell Division Control-Related Protein 1 antibodyAnti-Cdcrel-1 antibodyAnti-Peanut-Like Protein 1 antibodyAnti-SEPTIN5 antibodyAnti-PNUTL1 antibodyAnti-SEPT5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and TWF2 knockout (KO) 293T cells, using [KO Validated] TWF2 Rabbit polyclonal antibody (STJ11100774) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89710/358192/STJ11100774_1__12392.1713122508.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and TWF2 knockout (KO) 293T cells, using [KO Validated] TWF2 Rabbit polyclonal antibody (STJ11100774) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.")
