| Short Description : | Rabbit polyclonal SEPT11 (1-120) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:2000-1:4000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SEPTIN11 |
| Gene ID: | 55752 |
| Uniprot ID: | SEP11_HUMAN |
| Immunogen Region: | 1-120 |
| Immunogen Sequence: | MAVAVGRPSNEELRNLSLSG HVGFDSLPDQLVNKSTSQGF CFNILCVGETGIGKSTLMDT LFNTKFESDPATHNEPGVRL KARSYELQESNVRLKLTIVD TVGFGDQINKDDSYKPIVEY |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human Septin 11 (NP_060713.1). |
| Tissue Specificity | Widely expressed, except in leukocytes. |
| Function | Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity. During Listeria monocytogenes infection, not required for the bacterial entry process, but restricts its efficacy. |
| Protein Name | Septin-11 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonSynapseCell ProjectionDendritic SpineAxonPartly Colocalizes With Stress Fibers And MicrotubulesDuring Bacterial InfectionDisplays A Collar Shape Structure Next To Actin At The Pole Of Invading Bacteria |
| Alternative Antibody Names | Anti-Septin-11 antibodyAnti-SEPTIN11 antibodyAnti-SEPT11 antibody |
Information sourced from Uniprot.org
