| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SEPT11 (1-120) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:2000-1:4000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SEPTIN11 |
| Gene ID: |
55752 |
| Uniprot ID: |
SEP11_HUMAN |
| Immunogen Region: |
1-120 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human Septin 11 (NP_060713.1). |
| Immunogen Sequence: |
MAVAVGRPSNEELRNLSLSG HVGFDSLPDQLVNKSTSQGF CFNILCVGETGIGKSTLMDT LFNTKFESDPATHNEPGVRL KARSYELQESNVRLKLTIVD TVGFGDQINKDDSYKPIVEY |
| Tissue Specificity | Widely expressed, except in leukocytes. |
| Function | Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity. During Listeria monocytogenes infection, not required for the bacterial entry process, but restricts its efficacy. |
| Protein Name | Septin-11 |
| Cellular Localisation | CytoplasmCytoskeletonSynapseCell ProjectionDendritic SpineAxonPartly Colocalizes With Stress Fibers And MicrotubulesDuring Bacterial InfectionDisplays A Collar Shape Structure Next To Actin At The Pole Of Invading Bacteria |
| Alternative Antibody Names | Anti-Septin-11 antibodyAnti-SEPTIN11 antibodyAnti-SEPT11 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
