• Various whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with anti-SENP2 (PTR2320) antibody. The HRP-conjugated Goat anti- mouse IgG (H + L) antibody was used to detect the antibody. Lane 1: Hela Lane 2: HEK293 Lane 3: MDA-MB-231Predicted band size: 68kDaObserved band size: 65kDa
  • Various whole cell lysates (30ug) were separated by 10% SDS-PAGE, and the membrane was blotted with SENP2 antibody at 1ug/ml. The HRP-conjugated anti- mouseIgG antibody (Cat:STJ99665) was used to detect the antibody. Predicted band size: 68kDa

Anti-SENP2 antibody (430-526 aa) [PRT2320] (STJ193242)

SKU:
STJ193242

£46.00 - £226.00
Current Stock:
Host: Mouse
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Sentrin-specific protease 2 (430-526 aa) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: PRT2320
Conjugation: Unconjugated
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Dilution Range: WB 1:1000-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SENP2
Gene ID: 59343
Uniprot ID: SENP2_HUMAN
Immunogen Region: 430-526 aa
Specificity: This antibody detects endogenous levels of human SENP2
Immunogen: Synthesized peptide derived from the human SENP2 at the amino acid range 430-526
Function Protease that catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1. Plays a dynamic role in adipogenesis by desumoylating and promoting the stabilization of CEBPB. Acts as a regulator of the cGAS-STING pathway by catalyzing desumoylation of CGAS and STING1 during the late phase of viral infection.
Protein Name Sentrin-Specific Protease 2
Axam2
Smt3-Specific Isopeptidase 2
Smt3ip2
Sentrin/Sumo-Specific Protease Senp2
Database Links Reactome: R-HSA-3065679
Cellular Localisation Nucleus
Nuclear Pore Complex
Nucleus Membrane
Peripheral Membrane Protein
Nucleoplasmic Side
Cytoplasm
Shuttles Between Cytoplasm And Nucleus
Alternative Antibody Names Anti-Sentrin-Specific Protease 2 antibody
Anti-Axam2 antibody
Anti-Smt3-Specific Isopeptidase 2 antibody
Anti-Smt3ip2 antibody
Anti-Sentrin/Sumo-Specific Protease Senp2 antibody
Anti-SENP2 antibody
Anti-KIAA1331 antibody

Information sourced from Uniprot.org

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