| Short Description : | Rabbit polyclonal anti-Semaphorin-3A (C-Term) for use in ELISA and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | ELISA/WB |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | Antigen Affinity Purified |
| Dilution Range: | WB 1:1000 |
| Formulation: | PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol |
| Storage Instruction: | Storage at-20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at-20°C. |
| Gene Symbol: | SEMA3A |
| Gene ID: | 10371 |
| Uniprot ID: | SEM3A_HUMAN |
| Immunogen: | Semaphorin 3A synthetic peptide (coupled to carrier protein) corresponding to amino acids in the C-terminal region of human Sema3A. The sequence used has two amino acid differences from rat and mouse Sema3A, and has low homology to other semaphorin f |
| Immunogen Region: | C-Term |
| Immunogen Sequence: | Human |
| Specificity: | The antibody detects a 95kDa* protein corresponding to the apparent molecular mass of Sema3A on SDS-PAGE immunoblots of human recombinant Sema3A/Fc chimera and human A431 cells. |
| Tissue Specificity | Expressed in the dorsal root ganglia. |
| Function | Involved in the development of the olfactory system and in neuronal control of puberty. Induces the collapse and paralysis of neuronal growth cones. Could serve as a ligand that guides specific growth cones by a motility-inhibiting mechanism. Binds to the complex neuropilin-1/plexin-1. |
| Protein Name | Semaphorin-3aSemaphorin IiiSema Iii |
| Database Links | Reactome: R-HSA-399954Reactome: R-HSA-399955Reactome: R-HSA-399956 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Semaphorin-3a antibodyAnti-Semaphorin Iii antibodyAnti-Sema Iii antibodyAnti-SEMA3A antibodyAnti-SEMAD antibody |
Information sourced from Uniprot.org
