| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SEMA3C |
| Gene ID: | 10512 |
| Uniprot ID: | SEM3C_HUMAN |
| Immunogen Region: | 21-330 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-330 of human SEMA3C (NP_006370.1). |
| Immunogen Sequence: | GSSQPQARVYLTFDELRETK TSEYFSLSHHPLDYRILLMD EDQDRIYVGSKDHILSLNIN NISQEALSVFWPASTIKVEE CKMAGKDPTHGCGNFVRVIQ TFNRTHLYVCGSGAFSPVCT YLNRGRRSEDQVFMIDSKCE SGKGRCSFNPNVNTVSVMIN EELFSGMYIDFMGTDAAIFR SLTKRNAVRTDQHNSKWLSE PMFVDAHVIPDGTDPNDAKV YFFFKEKLTDNNRSTKQIH |
| Tissue Specificity | Expressed intensely in the heart, skeletal muscle, colon, small intestine, ovary, testis, and prostate. Faint expression ubiquitously among other organs, including brain. |
| Function | Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance. |
| Protein Name | Semaphorin-3cSemaphorin-ESema E |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Semaphorin-3c antibodyAnti-Semaphorin-E antibodyAnti-Sema E antibodyAnti-SEMA3C antibodyAnti-SEMAE antibody |
Information sourced from Uniprot.org