| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SEC23IP |
| Gene ID: | 11196 |
| Uniprot ID: | S23IP_HUMAN |
| Immunogen Region: | 600-940 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 600-940 of human SEC23IP (NP_009121.1). |
| Immunogen Sequence: | NLSKCPGPLAVANGVVKQLH FQEKQMPEEPKLTLDESYDL VVENKEVLTLQETLEALSLS EYFSTFEKEKIDMESLLMCT VDDLKEMGIPLGPRKKIANF VEHKAAKLKKAASEKKAVAA TSTKGQEQSAQKTKDMASLP SESNEPKRKLPVGACVSSVC VNYESFEVGAGQVSVAYNSL DFEPEIFFALGSPIAMFLTI RGVDRIDENYSLPTCKGFFN IYHPLDPVAYRLEPMIVPD |
| Tissue Specificity | Ubiquitously expressed with stronger levels detected in heart, liver and skeletal muscle. |
| Function | Plays a role in the organization of endoplasmic reticulum exit sites. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P) and phosphatidylinositol 5-phosphate (PI(5)P). |
| Protein Name | Sec23-Interacting ProteinP125 |
| Database Links | Reactome: R-HSA-204005 |
| Cellular Localisation | Cytoplasmic VesicleCopii-Coated Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideEndoplasmic Reticulum |
| Alternative Antibody Names | Anti-Sec23-Interacting Protein antibodyAnti-P125 antibodyAnti-SEC23IP antibodyAnti-MSTP053 antibody |
Information sourced from Uniprot.org