| Host: |
Rabbit |
| Applications: |
WB/IHC/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SEC14L2 (60-270) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000IHC-P 1:50-1:200IF/ICC 1:50-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SEC14L2 |
| Gene ID: |
23541 |
| Uniprot ID: |
S14L2_HUMAN |
| Immunogen Region: |
60-270 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 60-270 of human SEC14L2 (NP_001191133.1). |
| Immunogen Sequence: |
GRKVETITIIYDCEGLGLKH LWKPAVEAYGEFLCMFEENY PETLKRLFVVKAPKLFPVAY NLIKPFLSEDTRKKIMVLGA NWKEVLLKHISPDQVPVEYG GTMTDPDGNPKCKSKINYGG DIPRKYYVRDQVKQQYEHSV QISRGSSHQVEYEILFPGCV LRWQFMSDGADVGFGIFLKT KMGERQRAGEMTEVLPNQRY NSHLVPEDGTL |
| Tissue Specificity | Widely expressed. Strong expression in liver, brain and prostate. |
| Function | Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell. |
| Protein Name | Sec14-Like Protein 2Alpha-Tocopherol-Associated ProteinTapHtapSqualene Transfer ProteinSupernatant Protein FactorSpf |
| Cellular Localisation | CytoplasmNucleusCytoplasmic In Absence Of Alpha-TocopherolAnd Nuclear In Presence Of Alpha-Tocopherol |
| Alternative Antibody Names | Anti-Sec14-Like Protein 2 antibodyAnti-Alpha-Tocopherol-Associated Protein antibodyAnti-Tap antibodyAnti-Htap antibodyAnti-Squalene Transfer Protein antibodyAnti-Supernatant Protein Factor antibodyAnti-Spf antibodyAnti-SEC14L2 antibodyAnti-C22orf6 antibodyAnti-KIAA1186 antibodyAnti-KIAA1658 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
