Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-GTP-binding protein SAR1b (111-160 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SAR1B |
Gene ID: |
51128 |
Uniprot ID: |
SAR1B_HUMAN |
Immunogen Region: |
111-160 aa |
Specificity: |
Sar1B Polyclonal Antibody detects endogenous levels of Sar1B protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human SAR1B at the amino acid range 111-160 |
Function | GTP-binding protein involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex. Synergizes with the cargo receptor SURF4 to mediate the export of lipoproteins from the endoplasmic reticulum, thereby regulating lipoprotein delivery and the maintenance of lipid homeostasis. |
Protein Name | Gtp-Binding Protein Sar1bGtp-Binding Protein BGtbpb |
Database Links | Reactome: R-HSA-1655829Reactome: R-HSA-204005Reactome: R-HSA-2132295Reactome: R-HSA-5694530Reactome: R-HSA-8963888Reactome: R-HSA-9705671Reactome: R-HSA-983170 |
Cellular Localisation | Endoplasmic Reticulum MembranePeripheral Membrane ProteinGolgi ApparatusGolgi Stack MembraneAssociated With The Endoplasmic Reticulum And Golgi StacksIn Particular In The Juxta-Nuclear Golgi Region |
Alternative Antibody Names | Anti-Gtp-Binding Protein Sar1b antibodyAnti-Gtp-Binding Protein B antibodyAnti-Gtbpb antibodyAnti-SAR1B antibodyAnti-SARA2 antibodyAnti-SARB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance