Anti-SAP130 antibody (819-1048) (STJ115836)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SAP130 (819-1048) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SAP130 |
| Gene ID | 79595 |
| Uniprot ID | SP130_HUMAN |
| Immunogen Region | 819-1048 |
| Immunogen Sequence | LSMPTSDLPPGASPRKKPRK QQHVISTEEGDMMETNSTDD EKSTAKSLLVKAEKRKSPPK EYIDEEGVRYVPVRPRPPIT LLRHYRNPWKAAYHHFQRYS DVRVKEEKKAMLQEIANQKG VSCRAQGWKVHLCAAQLLQL TNLEHDVYERLTNLQEGIIP KKKAATDDDLHRINELIQGN MQRCKLVMDQISEARDSMLK VLDHKDRVLKLLNKNGTVKK VSKLKRKEKV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 819-1048 of human SAP130 (NP_078821.2). |
Additional Info
| Tissue Specificity | Expressed in various cancer cell ines. |
| Post Translational Modifications | Acetylated. Sumoylated with SUMO1. |
| Function | Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes. |
| Protein Name | Histone Deacetylase Complex Subunit Sap130130 Kda Sin3-Associated PolypeptideSin3-Associated Polypeptide P130 |
| Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-427413 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Histone Deacetylase Complex Subunit Sap130 antibodyAnti-130 Kda Sin3-Associated Polypeptide antibodyAnti-Sin3-Associated Polypeptide P130 antibodyAnti-SAP130 antibody |
Information sourced from Uniprot.org