| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Sterile alpha motif domain-containing protein 1 (418-468 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SAMD1 |
| Gene ID: |
90378 |
| Uniprot ID: |
SAMD1_HUMAN |
| Immunogen Region: |
418-468 aa |
| Specificity: |
This antibody detects endogenous levels of SAMD1 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human SAMD1 at the amino acid range 418-468 |
| Function | Unmethylated CpG islands (CGIs)-binding protein which localizes to H3K4me3-decorated CGIs, where it acts as a transcriptional repressor. Tethers L3MBTL3 to chromatin and interacts with the KDM1A histone demethylase complex to modulate H3K4me2 and H3K4me3 levels at CGIs. Plays a role in atherogenesis by binding with LDL on cell surface and promoting LDL oxidation which leads to the formation of foam cell. |
| Protein Name | Sterile Alpha Motif Domain-Containing Protein 1Sam Domain-Containing Protein 1Atherin |
| Cellular Localisation | NucleusChromosomeSecretedIn Atherosclerotic LesionsIt Is Found In The Extracellular Compartment And In Foam Cells Cytoplasm |
| Alternative Antibody Names | Anti-Sterile Alpha Motif Domain-Containing Protein 1 antibodyAnti-Sam Domain-Containing Protein 1 antibodyAnti-Atherin antibodyAnti-SAMD1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
