| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-S1PR3 (1-100) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S3MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
S1PR3 |
| Gene ID: |
1903 |
| Uniprot ID: |
S1PR3_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human S1PR3 (Q99500). |
| Immunogen Sequence: |
MATALPPRLQPVRGNETLRE HYQYVGKLAGRLKEASEGST LTTVLFLVICSFIVLENLMV LIAIWKNNKFHNRMYFFIGN LALCDLLAGIAYKVNILMSG |
| Tissue Specificity | Expressed in all tissues, but most abundantly in heart, placenta, kidney, and liver. |
| Function | Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. |
| Protein Name | Sphingosine 1-Phosphate Receptor 3S1p Receptor 3S1p3Endothelial Differentiation G-Protein Coupled Receptor 3Sphingosine 1-Phosphate Receptor Edg-3S1p Receptor Edg-3 |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-419408Reactome: R-HSA-9009391 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sphingosine 1-Phosphate Receptor 3 antibodyAnti-S1p Receptor 3 antibodyAnti-S1p3 antibodyAnti-Endothelial Differentiation G-Protein Coupled Receptor 3 antibodyAnti-Sphingosine 1-Phosphate Receptor Edg-3 antibodyAnti-S1p Receptor Edg-3 antibodyAnti-S1PR3 antibodyAnti-C9orf108 antibodyAnti-C9orf47 antibodyAnti-EDG3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
