Anti-S1PR3 antibody (1-100) [S3MR] (STJ11101433)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal S1PR3 (1-100) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S3MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:6000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | S1PR3 |
| Gene ID | 1903 |
| Uniprot ID | S1PR3_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MATALPPRLQPVRGNETLRE HYQYVGKLAGRLKEASEGST LTTVLFLVICSFIVLENLMV LIAIWKNNKFHNRMYFFIGN LALCDLLAGIAYKVNILMSG |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human S1PR3 (Q99500). |
Additional Info
| Tissue Specificity | Expressed in all tissues, but most abundantly in heart, placenta, kidney, and liver. |
| Function | Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. |
| Protein Name | Sphingosine 1-Phosphate Receptor 3S1p Receptor 3S1p3Endothelial Differentiation G-Protein Coupled Receptor 3Sphingosine 1-Phosphate Receptor Edg-3S1p Receptor Edg-3 |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-419408Reactome: R-HSA-9009391 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sphingosine 1-Phosphate Receptor 3 antibodyAnti-S1p Receptor 3 antibodyAnti-S1p3 antibodyAnti-Endothelial Differentiation G-Protein Coupled Receptor 3 antibodyAnti-Sphingosine 1-Phosphate Receptor Edg-3 antibodyAnti-S1p Receptor Edg-3 antibodyAnti-S1PR3 antibodyAnti-C9orf108 antibodyAnti-C9orf47 antibodyAnti-EDG3 antibody |
Information sourced from Uniprot.org