Western blot of rat hippocampal lysate showing specific immunolabeling of the ~48 kDa RXR-Gamma isotype.

Anti-RXRG antibody (Hinge region) [1373] (STJA0003769)

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STJA0003769-100
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Host: Mouse
Applications: WB
Reactivity: Human/Rat/Bovine/Mouse/Non-Human Primates
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-RXRG (Hinge region) is suitable for use in Western Blot research applications.
Clonality : Monoclonal
Clone ID : 1373
Conjugation: Unconjugated
Isotype: IgG1
Formulation: 100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol.
Purification: This antibody was protein g purified culture from supernatant.
Dilution Range: WB 1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RXRG
Gene ID: 6258
Uniprot ID: RXRG_HUMAN
Immunogen Region: Hinge region
Immunogen: Synthetic peptide corresponding to amino acid residues from the hinge region conjugated to KLH.
Tissue Specificity Expressed in aortic endothelial cells (at protein level).
Post Translational Modifications Acetylated by EP300.
Function Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid.
Protein Name Retinoic Acid Receptor Rxr-Gamma
Nuclear Receptor Subfamily 2 Group B Member 3
Retinoid X Receptor Gamma
Database Links Reactome: R-HSA-383280
Reactome: R-HSA-5362517
Cellular Localisation Nucleus
Cytoplasm
Alternative Antibody Names Anti-Retinoic Acid Receptor Rxr-Gamma antibody
Anti-Nuclear Receptor Subfamily 2 Group B Member 3 antibody
Anti-Retinoid X Receptor Gamma antibody
Anti-RXRG antibody
Anti-NR2B3 antibody

Information sourced from Uniprot.org

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