Anti-RXR beta antibody (Internal) (STJ70606)

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STJ70606-100
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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Mouse/Rat/Dog/Pig/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Goat polyclonal antibody anti-RXR beta (Internal) is suitable for use in ELISA and Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: Peptide ELISA: antibody detection limit dilution 1:128000.
WB: Approx 55kDa band observed in lysates of cell line A431 (calculated MW of 56.9kDa according to NP_068811.1). In transfected HEK293 transiently expressing RXRB a band of approx. 60kDa
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: RXRB
Gene ID: 6257
Uniprot ID: RXRB_HUMAN
Immunogen Region: Internal
Accession Number: NP_068811.1
Specificity: This antibody is expected to recognise an epitope corresponding to aa 70-83 of human RXR beta protein and does not cross-react with either RXR alpha or gamma.
Immunogen Sequence: CRDGMGDSGRDSRSP
Function Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE).
Protein Name Retinoic Acid Receptor Rxr-Beta
Nuclear Receptor Subfamily 2 Group B Member 2
Retinoid X Receptor Beta
Database Links Reactome: R-HSA-1989781
Reactome: R-HSA-383280
Reactome: R-HSA-5362517
Reactome: R-HSA-9029558
Reactome: R-HSA-9029569
Reactome: R-HSA-9031525
Reactome: R-HSA-9031528
Reactome: R-HSA-9623433
Reactome: R-HSA-9632974
Cellular Localisation Nucleus
Cytoplasm
Alternative Antibody Names Anti-Retinoic Acid Receptor Rxr-Beta antibody
Anti-Nuclear Receptor Subfamily 2 Group B Member 2 antibody
Anti-Retinoid X Receptor Beta antibody
Anti-RXRB antibody
Anti-NR2B2 antibody

Information sourced from Uniprot.org