| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Reticulon-1 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RTN1 |
| Gene ID: | 6252 |
| Uniprot ID: | RTN1_HUMAN |
| Specificity: | This antibody detects endogenous levels of RTN1 (Isoform RTN1-C) at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human RTN1 (Isoform RTN1-C) |
| Post Translational Modifications | Isoforms RTN1-A and RTN1-B are phosphorylated. |
| Function | Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity. |
| Protein Name | Reticulon-1Neuroendocrine-Specific Protein |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinGolgi Apparatus Membrane |
| Alternative Antibody Names | Anti-Reticulon-1 antibodyAnti-Neuroendocrine-Specific Protein antibodyAnti-RTN1 antibodyAnti-NSP antibody |
Information sourced from Uniprot.org