Anti-RRAS2 antibody (90-170 aa) (STJ191296)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 90-170
General Information
| Short Description | Rabbit polyclonal anti-Ras-related protein R-Ras2 (90-170 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RRAS2 |
| Gene ID | 22800 |
| Uniprot ID | RRAS2_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 90-170 |
| Immunogen Region | 90-170 aa |
| Specificity | RRAS2 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | May be post-translationally modified by both palmitoylation and polyisoprenylation. Fatty-acylation at Lys-192, Lys-194.lys-196 and Lys-197 is required for localization to the plasma membrane and activity. Defatty-acylated by SIRT6, affecting its localization to the plasma membrane. |
| Function | GTP-binding protein with GTPase activity, involved in the regulation of MAPK signaling pathway and thereby controlling multiple cellular processes. Regulates craniofacial development. |
| Protein Name | Ras-Related Protein R-Ras2Ras-Like Protein Tc21Teratocarcinoma Oncogene |
| Database Links | Reactome: R-HSA-9696273 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic SideGolgi Apparatus Membrane |
| Alternative Antibody Names | Anti-Ras-Related Protein R-Ras2 antibodyAnti-Ras-Like Protein Tc21 antibodyAnti-Teratocarcinoma Oncogene antibodyAnti-RRAS2 antibodyAnti-TC21 antibody |
Information sourced from Uniprot.org