| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Ras-related protein R-Ras2 (90-170 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RRAS2 |
| Gene ID: | 22800 |
| Uniprot ID: | RRAS2_HUMAN |
| Immunogen Region: | 90-170 aa |
| Specificity: | RRAS2 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 90-170 |
| Post Translational Modifications | May be post-translationally modified by both palmitoylation and polyisoprenylation. Fatty-acylation at Lys-192, Lys-194.lys-196 and Lys-197 is required for localization to the plasma membrane and activity. Defatty-acylated by SIRT6, affecting its localization to the plasma membrane. |
| Function | GTP-binding protein with GTPase activity, involved in the regulation of MAPK signaling pathway and thereby controlling multiple cellular processes. Regulates craniofacial development. |
| Protein Name | Ras-Related Protein R-Ras2Ras-Like Protein Tc21Teratocarcinoma Oncogene |
| Database Links | Reactome: R-HSA-9696273 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic SideGolgi Apparatus Membrane |
| Alternative Antibody Names | Anti-Ras-Related Protein R-Ras2 antibodyAnti-Ras-Like Protein Tc21 antibodyAnti-Teratocarcinoma Oncogene antibodyAnti-RRAS2 antibodyAnti-TC21 antibody |
Information sourced from Uniprot.org
