• Whole cell lysates of A431 were separated by 10% SDS-PAGE, and the membrane was blotted with anti-GSK3β (PTR2553) antibody. The HRP-conjugated Goat anti- mouse IgG (H + L) antibody was used to detect the antibody. Lane 1: A431Predicted band size: 46kDaObserved band size: 42kDa
  • Whole cell lysates of A431 were separated by 10% SDS-PAGE, and the membrane was blotted with anti-GSK3β (PTR2553) antibody. The HRP-conjugated Goat anti- mouse IgG (H + L) antibody was used to detect the antibody. Lane 1: A431Predicted band size: 46kDaObserved band size: 46kDa
  • Whole cell lysates of Hela were separated by 10% SDS-PAGE, and the membrane was blotted with anti-GSK3β (PTR2553) antibody. The HRP-conjugated Goat anti- mouse IgG (H + L) antibody was used to detect the antibody. Lane 1: HelaPredicted band size: 46kDaObserved band size: 46kDa

Anti-RRAD antibody (1-100) [PTR2260] (STJA0006261)

SKU:
STJA0006261

$64.80 - $340.20
Current Stock:
Host: Mouse
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-GTP-binding protein RAD (1-100) is suitable for use in Western Blot and ELISA research applications.
Clonality: Monoclonal
Clone ID: PTR2260
Conjugation: Unconjugated
Isotype: IgG1k
Formulation: Liquid in PBS containing 50% Glycerol and 0.05% Proclin 300.
Purification: The antibody was purified using affinity-chromatography using specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RRAD
Gene ID: 6236
Uniprot ID: RAD_HUMAN
Immunogen Region: 1-100
Specificity: This antibody detects endogenous levels of RRAD at Human
Immunogen: Synthesized peptide derived from human protein. AA range: 1-100
Tissue Specificity Most abundantly expressed in the heart. Also found in the skeletal muscle and lung. Lesser amounts in placenta and kidney. Also detected in adipose tissue. Overexpressed in muscle of type II diabetic humans.
Function May regulate basal voltage-dependent L-type Ca(2+) currents and be required for beta-adrenergic augmentation of Ca(2+) influx in cardiomyocytes, thereby regulating increases in heart rate and contractile force. May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane. Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D.
Protein Name Gtp-Binding Protein Rad
Rad1
Ras Associated With Diabetes
Database Links Reactome: R-HSA-9031628
Cellular Localisation Cell Membrane
Alternative Antibody Names Anti-Gtp-Binding Protein Rad antibody
Anti-Rad1 antibody
Anti-Ras Associated With Diabetes antibody
Anti-RRAD antibody
Anti-RAD antibody

Information sourced from Uniprot.org

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