| Host: | Rabbit |
| Applications: | WB/IHC/IF |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-RPS7 (1-194) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000IHC-P 1:50-1:200IF/ICC 1:10-1:100 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RPS7 |
| Gene ID: | 6201 |
| Uniprot ID: | RS7_HUMAN |
| Immunogen Region: | 1-194 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-194 of human RPS7 (NP_001002.1). |
| Immunogen Sequence: | MFSSSAKIVKPNGEKPDEFE SGISQALLELEMNSDLKAQL RELNITAAKEIEVGGGRKAI IIFVPVPQLKSFQKIQVRLV RELEKKFSGKHVVFIAQRRI LPKPTRKSRTKNKQKRPRSR TLTAVHDAILEDLVFPSEIV GKRIRVKLDGSRLIKVHLDK AQQNNVEHKVETFSGVYKKL TGKDVNFEFPEFQL |
| Post Translational Modifications | Phosphorylated by NEK6. Ubiquitinated. Deubiquitinated by DESI2, leading to its stabilization. |
| Function | Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Required for rRNA maturation. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. |
| Protein Name | Small Ribosomal Subunit Protein Es740s Ribosomal Protein S7 |
| Database Links | Reactome: R-HSA-156827Reactome: R-HSA-156902Reactome: R-HSA-1799339Reactome: R-HSA-192823Reactome: R-HSA-2408557Reactome: R-HSA-6790901Reactome: R-HSA-6791226Reactome: R-HSA-72649Reactome: R-HSA-72689Reactome: R-HSA-72695Reactome: R-HSA-72702Reactome: R-HSA-72706Reactome: R-HSA-72764Reactome: R-HSA-9010553Reactome: R-HSA-9633012Reactome: R-HSA-9735869Reactome: R-HSA-9754678Reactome: R-HSA-975956Reactome: R-HSA-975957 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeNucleusNucleolusAlthough Rps7 Is Functional Within The CytoplasmThe Assembly Of Ribosomal Subunits Occurs In The NucleusRps7 Nuclear Import Is Mediated By Ipo5/Ranbp5Ipo7/Ranbp7Kpnb1/Importin-Beta Or Tpno1/TrnColocalizes With Nek6 In The Centrosome |
| Alternative Antibody Names | Anti-Small Ribosomal Subunit Protein Es7 antibodyAnti-40s Ribosomal Protein S7 antibodyAnti-RPS7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
