| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RPS27 |
| Gene ID: | 6232 |
| Uniprot ID: | RS27_HUMAN |
| Immunogen Region: | 1-84 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-84 of human RPS27 (NP_001021.1). |
| Immunogen Sequence: | MPLAKDLLHPSPEEEKRKHK KKRLVQSPNSYFMDVKCPGC YKITTVFSHAQTVVLCVGCS TVLCQPTGGKARLTEGCSFR RKQH |
| Tissue Specificity | Expressed in a wide variety of actively proliferating cells and tumor tissues. |
| Function | Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Required for proper rRNA processing and maturation of 18S rRNAs. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. |
| Protein Name | Small Ribosomal Subunit Protein Es27 40s Ribosomal Protein S27 Metallopan-Stimulin 1 Mps-1 |
| Database Links | Reactome: R-HSA-141444 Reactome: R-HSA-156827 Reactome: R-HSA-156902 Reactome: R-HSA-1799339 Reactome: R-HSA-192823 Reactome: R-HSA-2408557 Reactome: R-HSA-2467813 Reactome: R-HSA-2500257 Reactome: R-HSA-5663220 Reactome: R-HSA-6791226 Reactome: R-HSA-68877 Reactome: R-HSA-72649 Reactome: R-HSA-72689 Reactome: R-HSA-72695 Reactome: R-HSA-72702 Reactome: R-HSA-72706 Reactome: R-HSA-72764 Reactome: R-HSA-9010553 Reactome: R-HSA-9633012 Reactome: R-HSA-9648025 Reactome: R-HSA-9735869 Reactome: R-HSA-9754678 Reactome: R-HSA-975956 Reactome: R-HSA-975957 |
| Cellular Localisation | Cytoplasm Nucleus Nucleolus |
| Alternative Antibody Names | Anti-Small Ribosomal Subunit Protein Es27 antibody Anti-40s Ribosomal Protein S27 antibody Anti-Metallopan-Stimulin 1 antibody Anti-Mps-1 antibody Anti-RPS27 antibody Anti-MPS1 antibody |
Information sourced from Uniprot.org