| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RPRD1A |
| Gene ID: | 55197 |
| Uniprot ID: | RPR1A_HUMAN |
| Immunogen Region: | 47-276 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 47-276 of human RPRD1A (NP_001290341.1). |
| Immunogen Sequence: | PVIVEAFKHVSSETDESCKK HLGRVLSIWEERSVYENDVL EQLKQALYGDKKPRKRTYEQ IKVDENENCSSLGSPSEPPQ TLDLVRALQDLENAASGDAA VHQRIASLPVEVQEVSLLDK ITDKESGERLSKMVEDACML LADYNGRLAAEIDDRKQLTR MLADFLRCQKEALAEKEHKL EEYKRKLARVSLVRKELRSR IQSLPDLSRLPNVTGSHMHL PFAGDIYSED |
| Function | Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle. |
| Protein Name | Regulation Of Nuclear Pre-Mrna Domain-Containing Protein 1aCyclin-Dependent Kinase Inhibitor 2b-Related ProteinP15ink4b-Related Protein |
| Database Links | Reactome: R-HSA-6807505 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Regulation Of Nuclear Pre-Mrna Domain-Containing Protein 1a antibodyAnti-Cyclin-Dependent Kinase Inhibitor 2b-Related Protein antibodyAnti-P15ink4b-Related Protein antibodyAnti-RPRD1A antibodyAnti-P15RS antibody |
Information sourced from Uniprot.org