Anti-ROR2 antibody (900-943) {FITC} (STJ502830)

SKU:
STJ502830-100

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Host: Rabbit
Applications: ELISA/IHC/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ROR2 (900-943) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: FITC
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.55-0.75 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
IHC: 1:50-1:150
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: ROR2
Gene ID: 4920
Uniprot ID: ROR2_HUMAN
Immunogen Region: 900-943
Immunogen: Synthetic peptide taken within amino acid region 900-943 on human ROR2 protein.
Function Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation. In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling.
Protein Name Tyrosine-Protein Kinase Transmembrane Receptor Ror2
Neurotrophic Tyrosine Kinase - Receptor-Related 2
Database Links Reactome: R-HSA-4086400
Reactome: R-HSA-5140745
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Tyrosine-Protein Kinase Transmembrane Receptor Ror2 antibody
Anti-Neurotrophic Tyrosine Kinase - Receptor-Related 2 antibody
Anti-ROR2 antibody
Anti-NTRKR2 antibody

Information sourced from Uniprot.org

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