| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-mRNA-capping enzyme is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RNGTT |
| Gene ID: |
8732 |
| Uniprot ID: |
MCE1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of RNGTT at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human RNGTT |
| Function | Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate. |
| Protein Name | Mrna-Capping EnzymeHcap1Hce Includes - Mrna 5'-Triphosphate MonophosphataseMrna 5'-Phosphatase - Mrna GuanylyltransferaseGtp--Rna GuanylyltransferaseGtase |
| Database Links | Reactome: R-HSA-167160Reactome: R-HSA-72086Reactome: R-HSA-77075 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Mrna-Capping Enzyme antibodyAnti-Hcap1 antibodyAnti-Hce Includes - Mrna 5'-Triphosphate Monophosphatase antibodyAnti-Mrna 5'-Phosphatase - Mrna Guanylyltransferase antibodyAnti-Gtp--Rna Guanylyltransferase antibodyAnti-Gtase antibodyAnti-RNGTT antibodyAnti-CAP1A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
