| Host: | Rabbit |
| Applications: | IF/ICC/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RNF149 |
| Gene ID: | 284996 |
| Uniprot ID: | RN149_HUMAN |
| Immunogen Region: | 200-300 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human RNF149 (NP_775918.2). |
| Immunogen Sequence: | SVVFVAIAFITMMIISLAWL IFYYIQRFLYTGSQIGSQSH RKETKKVIGQLLLHTVKHGE KGIDVDAENCAVCIENFKVK DIIRILPCKHIFHRICIDPW L |
| Function | E3 ubiquitin-protein ligase. Ubiquitinates BRAF, inducing its proteasomal degradation. |
| Protein Name | E3 Ubiquitin-Protein Ligase Rnf149Dna Polymerase-Transactivated Protein 2Ring Finger Protein 149Ring-Type E3 Ubiquitin Transferase Rnf149 |
| Cellular Localisation | MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Rnf149 antibodyAnti-Dna Polymerase-Transactivated Protein 2 antibodyAnti-Ring Finger Protein 149 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Rnf149 antibodyAnti-RNF149 antibodyAnti-DNAPTP2 antibody |
Information sourced from Uniprot.org