| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RLN2 |
| Gene ID: | 6019 |
| Uniprot ID: | REL2_HUMAN |
| Immunogen Region: | 25-185 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-185 of human RLN2 (NP_604390.1). |
| Immunogen Sequence: | DSWMEEVIKLCGRELVRAQI AICGMSTWSKRSLSQEDAPQ TPRPVAEIVPSFINKDTETI NMMSEFVANLPQELKLTLSE MQPALPQLQQHVPVLKDSSL LFEEFKKLIRNRQSEAADSS PSELKYLGLDTHSRKKRQLY SALANKCCHVGCTKRSLARF C |
| Tissue Specificity | Isoform 1 is expressed in the ovary during pregnancy. Also expressed in placenta, decidua and prostate. Isoform 2 is relatively abundant in placenta. It is in much lower abundance in the prostate gland. Not detected in the ovary. |
| Function | Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix. |
| Protein Name | Prorelaxin H2 Cleaved Into - Relaxin B Chain - Relaxin A Chain |
| Database Links | Reactome: R-HSA-418555Reactome: R-HSA-444821 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Prorelaxin H2 Cleaved Into - Relaxin B Chain - Relaxin A Chain antibodyAnti-RLN2 antibody |
Information sourced from Uniprot.org