• Western blot analysis of various lysates using RIN2 Rabbit polyclonal antibody (STJ115742) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-RIN2 antibody (596-895) (STJ115742)

SKU:
STJ115742

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-RIN2 (596-895) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RIN2
Gene ID: 54453
Uniprot ID: RIN2_HUMAN
Immunogen Region: 596-895
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 596-895 of human RIN2 (NP_061866.1).
Immunogen Sequence: HKCILKPLKGHVEAMLKDFH MADGSWKQLKENLQLVRQRN PQELGVFAPTPDFVDVEKIK VKFMTMQKMYSPEKKVMLLL RVCKLIYTVMENNSGRMYGA DDFLPVLTYVIAQCDMLELD TEIEYMMELLDPSLLHGEGG YYLTSAYGALSLIKNFQEEQ AARLLSSETRDTLRQWHKRR TTNRTIPSVDDFQNYLRVAF QEVNSGCTGKTLLVRPYITT EDVCQICAEKFKVGDPEEY
Tissue Specificity Widely expressed. Expressed in heart, kidney, lung placenta. Expressed at low level in skeletal muscle, spleen and peripheral blood.
Function Ras effector protein. May function as an upstream activator and/or downstream effector for RAB5B in endocytic pathway. May function as a guanine nucleotide exchange (GEF) of RAB5B, required for activating the RAB5 proteins by exchanging bound GDP for free GTP.
Protein Name Ras And Rab Interactor 2
Ras Association Domain Family 4
Ras Inhibitor Jc265
Ras Interaction/Interference Protein 2
Database Links Reactome: R-HSA-8876198
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Ras And Rab Interactor 2 antibody
Anti-Ras Association Domain Family 4 antibody
Anti-Ras Inhibitor Jc265 antibody
Anti-Ras Interaction/Interference Protein 2 antibody
Anti-RIN2 antibody
Anti-RASSF4 antibody

Information sourced from Uniprot.org

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