| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RIMS2 |
| Gene ID: | 9699 |
| Uniprot ID: | RIMS2_HUMAN |
| Immunogen Region: | 1-350 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human RIMS2 (NP_055492.3). |
| Immunogen Sequence: | MQFETLRQVCNSVLSHFHGV FSSPPNILQNELFGQTLNNA RKRSPSVSRDQNRRYDQREE REEYSQYATSDTAMPRSPSD YADRRSQHEPQFYEDSDHLS YRDSNRRSHRHSKEYIVDDE DVESRDEYERQRREEEYQSR YRSDPNLARYPVKPQPYEEQ MRIHAEVSRARHERRHSDVS LANADLEDSRISMLRMDRPS RQRSISERRAAMENQRSYSM ERTREAQGPSSYAQRTTNH |
| Tissue Specificity | Widely expressed. Expressed in melanocytes. In fetal tissues, predominantly expressed in the brain. In the retina, expressed in the outer plexiform layer (at protein level). In the cerebellum, expressed in Purkinje cells (at protein level). In the pancreas, expressed in Langerhans islets (at protein level). |
| Function | Rab effector involved in exocytosis. May act as scaffold protein. Plays a role in dendrite formation by melanocytes. |
| Protein Name | Regulating Synaptic Membrane Exocytosis Protein 2Rab-3-Interacting Molecule 2Rim 2Rab-3-Interacting Protein 3 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinSynapsePresynaptic Cell Membrane |
| Alternative Antibody Names | Anti-Regulating Synaptic Membrane Exocytosis Protein 2 antibodyAnti-Rab-3-Interacting Molecule 2 antibodyAnti-Rim 2 antibodyAnti-Rab-3-Interacting Protein 3 antibodyAnti-RIMS2 antibodyAnti-KIAA0751 antibodyAnti-RAB3IP3 antibodyAnti-RIM2 antibody |
Information sourced from Uniprot.org