Anti-RGS9BP antibody (1-107) (STJ11104878)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Regulator Of G-Protein Signaling 9-Binding Protein (1-107) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RGS9BP |
| Gene ID | 388531 |
| Uniprot ID | R9BP_HUMAN |
| Immunogen Region | 1-107 |
| Immunogen Sequence | MAREECKALLDGLNKTTACY HHLVLTVGGSADSQNLRQEL QKTRQKAQELAVSTCARLTA VLRDRGLAADERAEFERLWV AFSGCLDLLEADMRRALELG AAFPLHA |
| Specificity | Recombinant Protein corresponding to a sequence within amino acids 1-107 of human R9AP/RGS9BP (NP_997274.2). |
Additional Info
| Function | Regulator of G protein-coupled receptor (GPCR) signaling in phototransduction. Participates in the recovery phase of visual transduction via its interaction with RGS9-1 isoform. Acts as a membrane-anchor that mediates the targeting of RGS9-1 to the photoreceptor outer segment, where phototransduction takes place. Enhances the ability of RGS9-1 to stimulate G protein GTPase activity, allowing the visual signal to be terminated on the physiologically time scale. It also controls the proteolytic stability of RGS9-1, probably by protecting it from degradation. |
| Protein Name | Regulator Of G-Protein Signaling 9-Binding ProteinRgs9-Anchoring Protein |
| Database Links | Reactome: R-HSA-2514859 |
| Cellular Localisation | MembraneSingle-Pass Type Iv Membrane Protein |
| Alternative Antibody Names | Anti-Regulator Of G-Protein Signaling 9-Binding Protein antibodyAnti-Rgs9-Anchoring Protein antibodyAnti-RGS9BP antibodyAnti-R9AP antibody |
Information sourced from Uniprot.org