| Short Description : | Rabbit monoclonal anti-RGS6 (443-455 aa) for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | R02-1D3 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.3 mg/mL |
| Purification: | Affinity Purified |
| Dilution Range: | WB 1:500-1:1000 |
| Formulation: | 50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | RGS6 |
| Gene ID: | 9628 |
| Uniprot ID: | RGS6_HUMAN |
| Immunogen: | A synthetic peptide of human RGS6 |
| Immunogen Region: | 443-455 aa |
| Function | Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS6/GNB5 dimer enhances GNAO1 GTPase activity. |
| Protein Name | Regulator Of G-Protein Signaling 6Rgs6S914 |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-6814122 |
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane ProteinNucleusCell MembraneInteraction With Gnb5 Mediates Translocation To The Nucleus |
| Alternative Antibody Names | Anti-Regulator Of G-Protein Signaling 6 antibodyAnti-Rgs6 antibodyAnti-S914 antibodyAnti-RGS6 antibody |
Information sourced from Uniprot.org
