| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RGS5 |
| Gene ID: | 8490 |
| Uniprot ID: | RGS5_HUMAN |
| Immunogen Region: | 1-181 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-181 of human RGS5 (NP_003608.1). |
| Immunogen Sequence: | MCKGLAALPHSCLERAKEIK IKLGILLQKPDSVGDLVIPY NEKPEKPAKTQKTSLDEALQ WRDSLDKLLQNNYGLASFKS FLKSEFSEENLEFWIACEDY KKIKSPAKMAEKAKQIYEEF IQTEAPKEVNIDHFTKDITM KNLVEPSLSSFDMAQKRIHA LMEKDSLPRFVRSEFYQELI K |
| Function | Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. |
| Protein Name | Regulator Of G-Protein Signaling 5Rgs5 |
| Database Links | Reactome: R-HSA-416476Reactome: R-HSA-418594 |
| Cellular Localisation | Isoform 1: CytoplasmMembraneIsoform 2: Cytoplasm |
| Alternative Antibody Names | Anti-Regulator Of G-Protein Signaling 5 antibodyAnti-Rgs5 antibodyAnti-RGS5 antibody |
Information sourced from Uniprot.org
