Host: |
Rabbit |
Applications: |
IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Regulator of G-protein signaling 16 (141-190 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
RGS16 |
Gene ID: |
6004 |
Uniprot ID: |
RGS16_HUMAN |
Immunogen Region: |
141-190 aa |
Specificity: |
RGS16 Polyclonal Antibody detects endogenous levels of RGS16 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human RGS16 at the amino acid range 141-190 |
Post Translational Modifications | Palmitoylated on Cys-2 and/or Cys-12. Phosphorylated. Phosphorylation at Tyr-168 by EGFR enhances GTPase accelerating (GAP) activity toward GNAI1. |
Function | Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Plays an important role in the phototransduction cascade by regulating the lifetime and effective concentration of activated transducin alpha. May regulate extra and intracellular mitogenic signals. |
Protein Name | Regulator Of G-Protein Signaling 16Rgs16A28-Rgs14pRetinal-Specific RgsRgs-RHrgs-RRetinally Abundant Regulator Of G-Protein Signaling |
Database Links | Reactome: R-HSA-416476Reactome: R-HSA-418594Reactome: R-HSA-418597 |
Cellular Localisation | MembraneLipid-Anchor |
Alternative Antibody Names | Anti-Regulator Of G-Protein Signaling 16 antibodyAnti-Rgs16 antibodyAnti-A28-Rgs14p antibodyAnti-Retinal-Specific Rgs antibodyAnti-Rgs-R antibodyAnti-Hrgs-R antibodyAnti-Retinally Abundant Regulator Of G-Protein Signaling antibodyAnti-RGS16 antibodyAnti-RGSR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance