| Host: |
Rabbit |
| Applications: |
IHC/WB |
| Reactivity: |
Mouse/Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RGMB (Internal Region) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Lyophilised |
| Purification: |
IgG purified |
| Dilution Range: |
IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications. |
| Storage Instruction: |
Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: |
Rgmb |
| Gene ID: |
68799 |
| Uniprot ID: |
RGMB_MOUSE |
| Immunogen Region: |
Internal Region |
| Specificity: |
Specific for RGMB. |
| Immunogen: |
A synthetic peptide from internal region of mature mouse Repulsive guidance molecule B (RGMB, DRAGON) conjugated to an immunogenic carrier protein was used as the antigen. |
| Post Translational Modifications | GPI-anchored. Autocatalytically cleaved at low pH.the two chains remain linked via two disulfide bonds. |
| Function | Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system. Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling. Promotes neuronal adhesion. May inhibit neurite outgrowth. |
| Protein Name | Repulsive Guidance Molecule BDrg11-Responsive Axonal Guidance And Outgrowth Of NeuriteDragon |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorMembrane Raft |
| Alternative Antibody Names | Anti-Repulsive Guidance Molecule B antibodyAnti-Drg11-Responsive Axonal Guidance And Outgrowth Of Neurite antibodyAnti-Dragon antibodyAnti-Rgmb antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
